For optimum gene expression the adaptation of the codon usage of cloned DNA fragments is of capital importance.  

Our proprietary software GENEius¹ optimises and adapts amino acid or DNA sequences to the codon usage of a chosen organism.

Generally codon optimisation can improve gene expression in heterologous expression systems by avoiding rare codons and using all different codons with similar frequencies as they are used in highly expressed genes of the chosen organism. Furthermore unwanted motifs or secondary structures like repeat or hairpin structures can easily be avoided and the equal distribution of G and C bases can be achieved.

The efficiency of gene synthesis itself as well of further downstream applications is considerably improved!

• Sophisticated codon usage adaptation and sequence optimisation
• Secure data transfer
• Fast and easy ordering
• Convenient quote request or submission of quotes
• Tracking of orders
• Order or quote history
• Individual project request

Convenient online ordering of synthetic genes combined with GENEius benfits. >