NimbleGen Sequence Capture is a revolutionary way to perform targeted sequencing with next generation technology.

Sequence Capture arrays enable the selective enrichment of genomic regions from full-complexity genomic DNA. The method is applicable to large contiguous or non-contiguous genomic regions, whole exomes, or any other targeted regions you want to resequence.

• Target any region of interest
• High level of specificity and uniformity of data
• Improved coverage in repetitive regions
• Easy detection of small indels and sequence variants
• Save time and cost

Eurofins MWG Operon as a certified service provider combines powerful sequencing solutions with sequence capture to provide a seamless workflow for your resequencing studies.

 

© 2009 Roche NimbleGen, Inc.

 

1. The customer defines the target region and respective capture array
2. The genomic DNA sample is fragmented
3. The sample is hybridised to a NimbleGen Sequence capture array.
4. Unbound fragments are removed
5. The target-enriched pool is eluted and amplified
6. The enriched sample is ready for next gen sequencing
7. Data are delivered to the customer