NimbleGen Sequence Capture is a revolutionary way to perform targeted sequencing with next generation technology.
Sequence Capture arrays enable the selective enrichment of genomic regions from full-complexity genomic DNA. The method is applicable to large contiguous or non-contiguous genomic regions, whole exomes, or any other targeted regions you want to resequence.
- Target any region of interest
- High level of specificity and uniformity of data
- Improved coverage in repetitive regions
- Easy detection of small indels and sequence variants
- Save time and cost
Eurofins MWG Operon as a certified service provider combines powerful sequencing solutions with sequence capture to provide a seamless workflow for your resequencing studies.
© 2009 Roche NimbleGen, Inc.
- The customer defines the target region and respective capture array
- The genomic DNA sample is fragmented
- The sample is hybridised to a NimbleGen Sequence capture array.
- Unbound fragments are removed
- The target-enriched pool is eluted and amplified
- The enriched sample is ready for next gen sequencing
- Data are delivered to the customer