- Eurofins MWG Operon offers licensed1 custom siRNA and predesigned siRNA synthesis. Our proprietary siMAX™ technology allows us to produce high quality siRNA delivered in a fast turnaround time
- All siMAX™ siRNA molecules are delivered annealed, purified and ready to use.
- Each product is normalised to ensure optimum duplex generation. MALDI-TOF mass spectrometry and capillary gel electrophoresis (CGE) traces of each single strand are provided free with every order
- Multiple scales and different purification options are available. Our siRNA can be ordered in either the standard 21mer or 27mer format
- Eurofins MWG Operon’s Online Design Tool gives you access to design algorithms which provide siRNA sequences for optimum silencing efficiency
- Every siRNA candidate sequence is checked by BLASTx analysis to reduce off-target effects
- In addition, the secondary structure of the siRNA/mRNA target site can be previewed. This function allows you to select siRNA candidates in regions of optimal secondary structure in order to improve silencing efficiency.
1 Disclaimer
This product is licensed under European Patents 1144623, 1214945 and foreign equivalents from Alnylam Pharmaceuticals, Inc., Cambridge, USA and is provided only for use in academic and commercial research (excluding the evaluation or characterisation of this product as the potential basis for a siRNA-based drug) and not for any other commercial purposes. Information about licenses for commercial use (including discovery and development of siRNA-based drugs) is available from Alnylam Pharmaceuticals, Inc., 300 Third Street, Cambridge, MA 02142, USA.
This product is covered by patents US 6,506,559, continuations and foreign counterparts thereof and sold under license to MWG BIOTECH AG and Eurofins MWG Operon GmbH by the CARNEGIE INSTITUTION OF WASHINGTON, 1530 P Street, N.W., Washington, D.C. 20005-1910. The use of double stranded RNA material may require a separate license from the CARNEGIE INSTITUTION OF WASHINGTON.
