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Eurofinsdna.com > Products & Services > siRNA > siRNA Modifications
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siRNA Modifications

Eurofins MWG Operon offers a wide variety of 5´ and 3´ modifications on either the sense or antisense strands of siRNA duplexes.

Position5'3'
FAM+ 
HEX + 
TET+ 
CY3+ 
CY5+ 
Amino C6 + 
Biotin++
Cholesteryl+ 
Phosphate+ 
Amino C7 +
Biotin (TEG)  +
Fluorescin  +
 
PurificationHPLC1
Purity2

≥ 80%

Guaranteed Yield30.05 µmol5 nmol
0.20 µmol15 nmol
1.0 µM 30 nmol
Turnaround time5-7 days

1 Modified siRNA requires HPLC purification
2 Purity is based on capillary gel electrophoresis (CGE) analysis of the single strand before the duplex is annealed
3 Yield and purity may be lower for sequences with higher then 70% GC content, containing three or more purine stretches, or having strong secondary structure