siMAX^TM siRNA is available as pre-designed siRNA molecules for human, mouse and rat. Customised siRNA can be ordered by entering your known sequence or take advantage of our free Online Design Tool.

Two purification grades, desalted and HPLC, are available in three different scales. siRNA is delivered as a ready to use duplex in single tubes, as standard. 96well plating is available on request.

All siMAX^TM siRNA is delivered in 1 ml 5x siMAX^TM buffer (30mM HEPES, 100 mM KCl, 1mM MgCl 2, pH = 7.3).

siMAXTM	Custom		Pre- designed1	siMAX™ Controls2
Purification	Desalted	HPLC	HPLC	HPLC
Purity Level3	> 70%	> 95%	> 95%	> 95%
Deprotected	Yes	Yes	Yes	Yes
Duplexed	Yes	Yes	Yes	Yes
Ready to use	Yes	Yes	Yes	Yes
Turnaround time (working days)	5	7	7	7
1 Predesigned siMAXTM siRNAs are available for human, mouse and rat 2 Control duplexes, e.g. Lamin A/C 3 Purity levels are based on QC of single strand

As a standard, siRNA molecule are synthesised with dTdT overhang: (NN)-N 19 template (21mer, dTdT). It is also possible to order siRNAs with alternate overhangs, which you can select in the order menu of our online ordering system.

Synthesis Scales	Average Yields		Guaranteed Yields
siMAXTM Purification	Desalted	HPLC	Desalted	HPLC
50 nmol	15 nmol	8 nmol	10 nmol	5 nmol
200 nmol	100 nmol	45 nmol	60 nmol	30 nmol
1000 nmol	200 nmol	100 nmol	160 nmol	80 nmol

These siRNA molecules have no dTdT overhang or any sticky overhang at all. 27mers might show higher efficiency in comparison to the ‘classical’ 21mer siRNA in certain cases (Kim et al. in Nature Biotechnology 2005 23(2): 222-226).

Synthesis Scales	Average Yields		Guaranteed Yields
siMAXTM Purification	Desalted	HPLC	Desalted	HPLC
50 nmol	12 nmol	8 nmol	7 nmol	5 nmol
200 nmol	60 nmol	30 nmol	40 nmol	20 nmol
1000 nmol	100 nmol	50 nmol	80 nmol	40 nmol